null
SMILES CNc1nn2c3CCN(C)Cc3cnc2c1S(=O)(=O)c1ccccc1
InChI Key InChIKey=OSHBEPOEBKFEEK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 103506
Affinity DataKi: 0.389nM IC50: 0.837nMAssay Description:The screening of the disclosed compounds for their potential ability to interact with serotonin 5-HT6 receptors was carried out b the method of radio...More data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptor expressed in HeLa cells after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HE293 cells assessed as inhibition of serotonin-induced cAMP accumulation after 2...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.42E+4nMAssay Description:Inhibition of human recombinant ERG channel expressed in HEK297 cells after 3 to 8 mins by voltage clamp assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.16E+3nMAssay Description:Antagonist activity at human recombinant 5HT2B receptor expressed in HEK293 cells assessed as inhibition of alphamethyl5HT-induced intracellular calc...More data for this Ligand-Target Pair