null

SMILES [H][C@@]1(NC(=O)[C@@H](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OC(C)(C)C)Cc2c(F)c(F)c(F)c(F)c2F)[C@H](O)Cc2ccccc12

InChI Key InChIKey=LUXWCCSCNDRTSF-BDRWXFPQSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1041   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1041(CHEMBL47514 | Hydroxyethylene dipeptide isostere 3...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 5.5 T: 2°CAssay Description:Assay of HIV protease inhibition was performed by peptide cleavage using the substrate Val-Ser-Gln-Asn-beta-naphthylalanine*Pro-Ile-Val. Products of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N877ZCPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Universidad de Alcal£

Curated by ChEMBL
LigandPNGBDBM1041(CHEMBL47514 | Hydroxyethylene dipeptide isostere 3...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RTNPubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Universidad de Alcal£

Curated by ChEMBL
LigandPNGBDBM1041(CHEMBL47514 | Hydroxyethylene dipeptide isostere 3...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:In vitro inhibition of HIV-1 proteaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23T9G8MPubMed