null
SMILES Oc1ccc(cc1)-n1ccnc1
InChI Key InChIKey=CYKCUAPYWQDIKR-UHFFFAOYSA-N
PDB links: 4 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 105193
Affinity DataIC50: 1.00E+6nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.00E+6nMAssay Description:Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*STAR
Curated by ChEMBL
A*STAR
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*STAR
Curated by ChEMBL
A*STAR
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Takeda California, Inc.
Curated by ChEMBL
Takeda California, Inc.
Curated by ChEMBL
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair