null

SMILES CN(C)C1CCC(=CC1)c1c[nH]c2ccc(cc12)N=C(N)c1cccs1

InChI Key InChIKey=BCUSKDWPXMSSRG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 106722   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348J0KUS Patent
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 5.14E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348J0KUS Patent
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
NeurAxon Inc.

Curated by ChEMBL
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 5.14E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 4.71E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 4.71E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
NeurAxon, Inc.

US Patent
LigandPNGBDBM106722(CHEMBL2036264 | US8586620, 114)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5H2VPubMed