null

SMILES Cc1nc(Cl)cc(Nc2cccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)n1

InChI Key InChIKey=OQNAEPJXWHOMFY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107673   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107673(1-(3-(6-Chloro-2-methylpyrimidin-4-ylamino)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 298nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107673(1-(3-(6-Chloro-2-methylpyrimidin-4-ylamino)phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 722nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed