null

SMILES Cc1nc(Nc2cccc(NC(=O)Nc3ccc(F)c(Cl)c3)c2)cc(n1)N1CCOCC1

InChI Key InChIKey=AQMQQBLCOUAJDA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107674   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107674(1-(3-Chloro-4-fluorophenyl)-3-(3-(2-methyl- 6-morp...)copy SMILEScopy InChI
Affinity DataIC50: 626nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107674(1-(3-Chloro-4-fluorophenyl)-3-(3-(2-methyl- 6-morp...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed