null

SMILES CN1CCN(CC1)c1cc(Nc2cccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)nc(C)n1

InChI Key InChIKey=ITLPVLLAPQMEHN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107676   

TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107676(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)copy SMILEScopy InChI
Affinity DataIC50: 7.17E+3nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry, 1111 Zhongshan North One Road, Hongkou District, Shanghai, 200437, China

LigandPNGBDBM107676(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(3-(2- me...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Compounds were prepared in DMSO at 10mmol/L and serially diluted in a 96-well plate as the source plate. The intermediate plate consists of 4µL...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MHMPubMed