null

SMILES OC(=O)C(=O)CC(=O)c1c[nH]c2ccc(Cl)cc12

InChI Key InChIKey=NVTRJKGWECZIQW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 107693   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Institute of Pharmacy, Nirma University, Ahmedabad, 382 481, India.

LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4VSWPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Messina

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BR1PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Messina

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7HDKPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Messina

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibitory effect on strand transfer of proviral DNA into host DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TPDPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Messina

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of HIV1 recombinant integraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7HDKPubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università di Messina

Curated by ChEMBL
LigandPNGBDBM107693((2Z)-4-(5-chloro-1H-indol-3-yl)-2-hydroxy-4-oxobut...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitory effect on 3'-processing(3'-P) of proviral DNA in an extracellular HIV-1 integrase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26D5TPDPubMed