null

SMILES OCCOc1cccc(CN2CC[C@H](C2)Nc2cccc3cnccc23)c1

InChI Key InChIKey=HRCKLYFDWWYCLS-LJQANCHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 108025   

TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA

LigandBDBM108025(US8604218, 2.039)copy SMILEScopy InChI

Affinity DataKi:  5nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA

LigandBDBM108025(US8604218, 2.039)copy SMILEScopy InChI

Affinity DataKi:  14nMMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA

LigandBDBM108025(US8604218, 2.039)copy SMILEScopy InChI

Affinity DataIC50: 101nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TJDUS Patent