null

SMILES CC(C)(C)C(=O)Nc1cccc(c1)-c1ccc2nc(-c3cccnc3N)n(-c3ccc(cc3)C3(N)CCC3)c2n1

InChI Key InChIKey=YQFLDUBZECPVCJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 108426   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataKd:  0.400nMpH: 7.5 T: 2°CAssay Description:Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Luminesce...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataKd:  0.400nMAssay Description:Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W957W7US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule, Inc.

US Patent
LigandPNGBDBM108426(US8609688, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMpH: 8.0 T: 2°CAssay Description:AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen™ (Amplified Lum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H41Q2MUS Patent