null

SMILES CC(C)(C)c1ccc(cc1)C(=O)NCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=MLMBOLOCASDIAK-UHFFFAOYSA-N

PDB links: 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 10894   

TargetCARBONIC ANHYDRASE(Helicobacter pylori J99)
Kochi Medical School

LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)copy SMILEScopy InChI
Affinity DataKi:  62nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TQBPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)copy SMILEScopy InChI
Affinity DataKi:  127nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TQBPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kochi Medical School

LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)copy SMILEScopy InChI
Affinity DataKi:  1.33E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2TQBPubMed
TargetBile acid receptor(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N3003WPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM10894(4-(4-tert-Butylphenylcarboxamidomethyl)benzenesulf...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human sEH using PHOME as substrate preincubated for 30 mins followed by substrate addition measured for 30 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N3003WPubMed