null

SMILES NS(=O)(=O)c1cc2C=CN(CCN3CCOCC3)S(=O)(=O)c2s1

InChI Key InChIKey=KRJXNTFQVBUWBY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11394   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11394(2-[2-(4-Morpholinyl)ethyl]-2H-thieno[3,2-e]-1,2-th...)copy SMILEScopy InChI
Affinity DataKi:  0.320nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11394(2-[2-(4-Morpholinyl)ethyl]-2H-thieno[3,2-e]-1,2-th...)copy SMILEScopy InChI
Affinity DataIC50: 15.2nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11394(2-[2-(4-Morpholinyl)ethyl]-2H-thieno[3,2-e]-1,2-th...)copy SMILEScopy InChI
Affinity DataIC50: 0.820nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed