null

SMILES NS(=O)(=O)c1cc2C=C(CN3CCOCC3)N(C3CCCCC3)S(=O)(=O)c2s1

InChI Key InChIKey=HZWDJRHOANOYLB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11413   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11413(2-Cyclohexyl-3-[(4-morpholinyl)methyl]-2H-thieno[3...)copy SMILEScopy InChI
Affinity DataKi:  0.310nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11413(2-Cyclohexyl-3-[(4-morpholinyl)methyl]-2H-thieno[3...)copy SMILEScopy InChI
Affinity DataIC50: 49.5nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11413(2-Cyclohexyl-3-[(4-morpholinyl)methyl]-2H-thieno[3...)copy SMILEScopy InChI
Affinity DataIC50: 0.790nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed