null

SMILES COc1cccc(c1)N1C(CNCCO)=Cc2cc(sc2S1(=O)=O)S(N)(=O)=O

InChI Key InChIKey=PDRINFGFCMWHJP-UHFFFAOYSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11421   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11421(2-(3-Methoxyphenyl)-3-[(2-hydroxyethylamino)methyl...)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11421(2-(3-Methoxyphenyl)-3-[(2-hydroxyethylamino)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.16nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed