null
SMILES OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
InChI Key InChIKey=SYOKIDBDQMKNDQ-XWTIBIIYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 103 hits for monomerid = 11695
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of DPP4 in human plasma using Gly-Pro-AMC as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrate preincubate...More data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataKi: 1.34E+3nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 51nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 51nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of DPP4 in presence of 50% human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration against dipeptidyl-peptidase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against DPP-II [Quiescent cell proline dipeptidase] or DPP-VIIMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibitory concentration against Dipeptidyl-peptidase 8More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibitory concentration against Dipeptidyl-peptidase IV [DPP-IV]More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant DPP4 expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of DPP9 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of FAP (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP7 (unknown origin) expressed in baculovirus expression system using Nle-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of DPP8 (unknown origin) expressed in baculovirus expression system using Ala-Pro-AMC as substrate by continuous fluorometric assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of DPP9 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of DPP8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DPP2 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant DPP4 by fluorescence assayMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Dainippon Sumitomo Pharma Co., Ltd
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DPP2More data for this Ligand-Target Pair