null
SMILES Fc1cc(I)ccc1Nc1ccnc2cc(Cl)ccc12
InChI Key InChIKey=SGYXYQQGWNUEIG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 120364
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Affinity DataIC50: 580nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Affinity DataIC50: 3.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (fumarate)(Saccharomyces cerevisiae)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College
US Patent
Affinity DataIC50: 1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair