null

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C(C)C)P(O)(O)=O

InChI Key InChIKey=BZVYQWLRCHLAGK-KRWDZBQOSA-N

PDB links: 1 PDB ID matches this monomer. 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 12073   

TargetNeutrophil collagenase(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12073((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)copy SMILEScopy InChI
Affinity DataKi:  700nM ΔG°:  -8.39kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12073((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nM ΔG°:  -8.07kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12073((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)copy SMILEScopy InChI
Affinity DatapH: 7.5 T: 2°CAssay Description:Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348HM7PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12073((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V4TPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Istituto di Cristallografia

LigandPNGBDBM12073((S)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair