null

SMILES CC(C)c1c(OC2CCCCC2)c2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=OQCFORGSZJSAEL-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12079   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12079(6-Chloro-4-cyclohexyloxy-3-isopropylquinol-2-one |...)copy SMILEScopy InChI
Affinity DataIC50: 630nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,L687I]/[588-1147,L687I](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12079(6-Chloro-4-cyclohexyloxy-3-isopropylquinol-2-one |...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
University of Oxford

LigandPNGBDBM12079(6-Chloro-4-cyclohexyloxy-3-isopropylquinol-2-one |...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair