null

SMILES COc1ccc(Cl)c(Nc2ncnc3cc(OCCCN4CCN(C)CC4)cc(OC4CCOCC4)c23)c1

InChI Key InChIKey=KSOSADFISSODEE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12243   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM12243(AZD0530 analogue 21 | N-(2-chloro-5-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F5XPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM12243(AZD0530 analogue 21 | N-(2-chloro-5-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F5XPubMed