null

SMILES CCOC(=O)N1CCC(CC1)Nc1ncc(C(=O)c2ccccc2C)c(N)n1

InChI Key InChIKey=KKFAWSRIYBKLKA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12614   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

LigandPNGBDBM12614(2,4-Diamino-5-ketopyrimidine 32 | 4-[4-Amino-5-(2-...)copy SMILEScopy InChI
Affinity DataKi:  665nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4VB2PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

LigandPNGBDBM12614(2,4-Diamino-5-ketopyrimidine 32 | 4-[4-Amino-5-(2-...)copy SMILEScopy InChI
Affinity DataKi:  1.11E+3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4VB2PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

LigandPNGBDBM12614(2,4-Diamino-5-ketopyrimidine 32 | 4-[4-Amino-5-(2-...)copy SMILEScopy InChI
Affinity DataKi:  2.17E+3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4VB2PubMed