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SMILES CCOc1ccccc1C(=O)c1cnc(NC2CCN(CC2)C(C)=O)nc1N

InChI Key InChIKey=OBDPIVSOXGXWQB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12615   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

LigandPNGBDBM12615(1-[4-({4-amino-5-[(2-ethoxyphenyl)carbonyl]pyrimid...)copy SMILEScopy InChI
Affinity DataKi:  986nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4VB2PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

LigandPNGBDBM12615(1-[4-({4-amino-5-[(2-ethoxyphenyl)carbonyl]pyrimid...)copy SMILEScopy InChI
Affinity DataKi:  2.03E+3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4VB2PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

LigandPNGBDBM12615(1-[4-({4-amino-5-[(2-ethoxyphenyl)carbonyl]pyrimid...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMAssay Description:Enzymes were assayed with retinoblastoma substrate in 384-well plates containing diluted test compounds. Final ATP concentration was 3x the respectiv...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4VB2PubMed