null

SMILES Nc1noc2ccc(cc12)-n1nc(cc1C(=O)Nc1ccc(cc1F)C(=O)N1CCCC1)C(F)(F)F

InChI Key InChIKey=XFHPQLVMJVEBAR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12664   

TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12664(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...)copy SMILEScopy InChI
Affinity DataKi:  0.920nM ΔG°:  -12.2kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK19K9PubMed
TargetSerine protease 1(Bos taurus (bovine))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12664(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...)copy SMILEScopy InChI
Affinity DataKi: >5.20E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK19K9PubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM12664(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-5-[...)copy SMILEScopy InChI
Affinity DataKi:  8.00E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK19K9PubMed