null

SMILES CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(OC(C)C)cc1

InChI Key InChIKey=HBUCOYMWRVERSG-UHFFFAOYSA-N

PDB links: 4 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13092   

TargetStromelysin-1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM13092(CGS 27023A Analog 20 | N-hydroxy-2-[(2-methylpropy...)copy SMILEScopy InChI
Affinity DataKi:  336nM ΔG°:  -9.18kcal/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FC7PubMed
TargetStromelysin-1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM13092(CGS 27023A Analog 20 | N-hydroxy-2-[(2-methylpropy...)copy SMILEScopy InChI
Affinity DataKi:  339nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571DBDPubMed
TargetCollagenase ColH(Hathewaya histolytica)TBA
LigandPNGBDBM13092(CGS 27023A Analog 20 | N-hydroxy-2-[(2-methylpropy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
In DepthDetails
TargetGelatinase()TBA
LigandPNGBDBM13092(CGS 27023A Analog 20 | N-hydroxy-2-[(2-methylpropy...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMMore data for this Ligand-Target Pair
In DepthDetails