null
SMILES COc1ccc(cc1)S(=O)(=O)N(CCc1ccccc1)CC(=O)NO
InChI Key InChIKey=HYKIXGPXDGBTKU-UHFFFAOYSA-N
PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 13095
Affinity DataKi: 66nM ΔG°: -10.2kcal/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute for Cell Therapy and Immunology IZI
Curated by ChEMBL
Fraunhofer Institute for Cell Therapy and Immunology IZI
Curated by ChEMBL
Affinity DataIC50: 4.29E+4nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair