null

SMILES COc1ccc(cc1)S(=O)(=O)N(CCc1ccccc1)CC(=O)NO

InChI Key InChIKey=HYKIXGPXDGBTKU-UHFFFAOYSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13095   

TargetStromelysin-1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM13095(CGS 27023A Analog 23 | N-hydroxy-2-[(4-methoxybenz...)copy SMILEScopy InChI
Affinity DataKi:  66nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2FC7PubMed
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute for Cell Therapy and Immunology IZI

Curated by ChEMBL
LigandPNGBDBM13095(CGS 27023A Analog 23 | N-hydroxy-2-[(4-methoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 4.29E+4nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5WH0PubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
FibroGen Inc.

Curated by ChEMBL
LigandPNGBDBM13095(CGS 27023A Analog 23 | N-hydroxy-2-[(4-methoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of PCP after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22808SMPubMed