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SMILES [#6]-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-c1cc2ccccc2s1

InChI Key InChIKey=KVEKZKVOVRZPMP-ZRBLBEILSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14111   

TargetSerine protease 1(Bos taurus (bovine))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14111((2S)-N-[(2S)-1-(1-benzothiophen-2-yl)-5-carbamimid...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Trypsin-catalyzed hydrolysis rates were measured spectrophotometrically using bovine trypsin, a chromogenic substrate in aqueous buffer, and a microp...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0658XPubMed
TargetSerine protease 1(Bos taurus (bovine))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14111((2S)-N-[(2S)-1-(1-benzothiophen-2-yl)-5-carbamimid...)copy SMILEScopy InChI
Affinity DataKi:  1.34E+3nMAssay Description:Inhibition of bovine trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3208PubMed
TargetProthrombin(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14111((2S)-N-[(2S)-1-(1-benzothiophen-2-yl)-5-carbamimid...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human alpha-thrombin.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B3208PubMed
TargetProthrombin(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14111((2S)-N-[(2S)-1-(1-benzothiophen-2-yl)-5-carbamimid...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9BNHPubMed
TargetProthrombin(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14111((2S)-N-[(2S)-1-(1-benzothiophen-2-yl)-5-carbamimid...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nM IC50: 1.30E+4nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0658XPubMed
TargetProthrombin(Homo sapiens (Human))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM14111((2S)-N-[(2S)-1-(1-benzothiophen-2-yl)-5-carbamimid...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HN2PubMed