null

SMILES Cc1cccc(NC(=O)C23CCC(C2)(CCC3)NC(=O)c2cccc(Cl)c2)n1

InChI Key InChIKey=AXIQDNJOMGBWRL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 141509   

TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM141509(US8921370, 176 | US9656975, 176)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5PVMUS Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM141509(US8921370, 176 | US9656975, 176)copy SMILEScopy InChI
Affinity DataKi:  500nM ΔG°:  -8.59kcal/molepH: 7.4 T: 2°CAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol. Pharmacol., 2003, 64, 731-740] with slight modifications, including that a r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5S3CUS Patent
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM141509(US8921370, 176 | US9656975, 176)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5PVMUS Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
H. Lundbeck A/S

US Patent
LigandPNGBDBM141509(US8921370, 176 | US9656975, 176)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 7.4 T: 2°CAssay Description:The cDNA for rat metabotropic glutamate receptor 5 (rmGluR5) and the cDNA for human metabotropic glutamate receptor 5 (rmGluR5) were generous gifts f...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5S3CUS Patent