null

SMILES Cn1ccc(COc2ccc3nc(C4CCCC[C@H]4C(O)=O)n(Cc4ccc(Br)cc4)c3c2)n1

InChI Key InChIKey=RISBHTOVLROQFG-FOIFJWKZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 145686   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM145686(US8952177, 40 | US8952177, 41 | US9089569, 41 | US...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73CFWUS Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM145686(US8952177, 40 | US8952177, 41 | US9089569, 41 | US...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85DBUS Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM145686(US8952177, 40 | US8952177, 41 | US9089569, 41 | US...)copy SMILEScopy InChI
Affinity DataKi:  3.90nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52MSCUS Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM145686(US8952177, 40 | US8952177, 41 | US9089569, 41 | US...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85DBUS Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM145686(US8952177, 40 | US8952177, 41 | US9089569, 41 | US...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52MSCUS Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM145686(US8952177, 40 | US8952177, 41 | US9089569, 41 | US...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73CFWUS Patent