null

SMILES CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2cccc3ccccc23)n1

InChI Key InChIKey=VZRWGPCOHZYQEP-HNAYVOBHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 146000   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM146000(US8957068, 35)copy SMILEScopy InChI
Affinity DataIC50: 248nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TD9W28US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM146000(US8957068, 35)copy SMILEScopy InChI
Affinity DataIC50: 250nMMore data for this Ligand-Target Pair
In DepthDetails
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Novartis AG

US Patent
LigandPNGBDBM146000(US8957068, 35)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
In DepthDetails