null
SMILES COc1ccccc1[C@H](C)Nc1nccc(n1)N1[C@H](COC1=O)C(C)C
InChI Key InChIKey=KDESFVQFLBRKMV-DZGCQCFKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 146055
Affinity DataIC50: 272nMpH: 7.4 T: 2°CAssay Description:Mutant IDH1 R132H catalytic activity was monitored using the quantitative liquid chromatography/mass spectrometry (LC-MS) detection of 2-HG, a produc...More data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
Affinity DataIC50: 275nMpH: 7.5 T: 2°CAssay Description:The IDH1 (R132H) mutant catalyzes the reduced form of NADP+ (NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide ph...More data for this Ligand-Target Pair