null

SMILES Fc1ccc(Sc2nc3CNC(=O)N(c3cc2C2=CCNCC2)c2c(Cl)cccc2Cl)c(F)c1

InChI Key InChIKey=PZUXNWPJBLCJKB-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15243   

TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM15243(1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulf...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14 [G110D](Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM15243(1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulf...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14 [G110A](Mus musculus (mouse))
Merck Research Laboratories

LigandPNGBDBM15243(1-(2,6-dichlorophenyl)-6-[(2,4-difluorophenyl)sulf...)copy SMILEScopy InChI
Affinity DataIC50: 61nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with wild-type or mutant p38alpha enzymes, and substrates in the presence ATP/[gam...More data for this Ligand-Target Pair