null

SMILES Cc1noc(n1)-c1cc2cc(C)ccc2nc1N1CCC(CC1)NCC1CC1

InChI Key InChIKey=IIVRURVOTPPDFG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 157256   

TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM157256(US10118915, Compound 433 | US9682966, 433)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2610XHQUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM157256(US10118915, Compound 433 | US9682966, 433)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G00US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM157256(US10118915, Compound 433 | US9682966, 433)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4N6QPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM157256(US10118915, Compound 433 | US9682966, 433)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at GAL4-VP16-fused DOR (unknown origin) expressed in human U2OS cells assessed as inhibition of DAMGO-induced beta-arrestin migra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4N6QPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM157256(US10118915, Compound 433 | US9682966, 433)copy SMILEScopy InChI
Affinity DataIC50: 829nMAssay Description:Antagonist activity at GAL4-VP16-fused MOR (unknown origin) expressed in human U2OS cells assessed as inhibition of DAMGO-induced beta-arrestin migra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4N6QPubMed