null

SMILES NC1=N[C@]2(COC[C@@]2(F)CO1)c1cc(NC(=O)c2ccc(cn2)[N+]#[C-])ccc1F

InChI Key InChIKey=DMJSMZBBMSPGKV-RTBURBONSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158180   

TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM158180(US9029367, 34)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z4344US Patent