null

SMILES Cc1noc(n1)-c1cc(C)cnc1N1CC[C@H](NC2CCCCC2)[C@@H](O)C1

InChI Key InChIKey=GAFFUWMMWKYJFF-ROUUACIJSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 159083   

TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM159083(US10118915, Compound 542 | US9682966, 542)copy SMILEScopy InChI
Affinity DataIC50: 32nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2610XHQUS Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM159083(US10118915, Compound 542 | US9682966, 542)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G00US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM159083(US10118915, Compound 542 | US9682966, 542)copy SMILEScopy InChI
Affinity DataIC50: 2.41E+3nMAssay Description:Antagonist activity at GAL4-VP16-fused DOR (unknown origin) expressed in human U2OS cells assessed as inhibition of DAMGO-induced beta-arrestin migra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4N6QPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM159083(US10118915, Compound 542 | US9682966, 542)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Antagonist activity at GAL4-VP16-fused MOR (unknown origin) expressed in human U2OS cells assessed as inhibition of DAMGO-induced beta-arrestin migra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4N6QPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM159083(US10118915, Compound 542 | US9682966, 542)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at GAL4-VP16-fused KOR (unknown origin) expressed in human U2OS cells co-expressing Tango-OPRK1-BLA assessed as inhibition of U-5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4N6QPubMed