null

SMILES COc1cc(OC)cc(c1)C#Cc1nn(CC2CN(C2)C(=O)C=C)c2ncnc(N)c12

InChI Key InChIKey=NLNSWQPNSJQAHU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 161416   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161416(US10124003, Ex. Compound 29 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161416(US10124003, Ex. Compound 29 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM161416(US10124003, Ex. Compound 29 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161416(US10124003, Ex. Compound 29 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319ZZFUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161416(US10124003, Ex. Compound 29 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In DepthDetails
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161416(US10124003, Ex. Compound 29 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 9.30nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent