null

SMILES COc1cc(OC)cc(c1)C#Cc1cn([C@H]2CCN(C2)C(=O)\C=C\CN2CC[C@@H](F)C2)c2ncnc(N)c12

InChI Key InChIKey=HUQYNBRBASHDJY-DTDVHRGSSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 161435   

TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161435(US10124003, Ex. Compound 49 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMpH: 7.5 T: 2°CAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XW4HJVUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161435(US10124003, Ex. Compound 49 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161435(US10124003, Ex. Compound 49 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319ZZFUS Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161435(US10124003, Ex. Compound 49 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161435(US10124003, Ex. Compound 49 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N26F5US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Taiho Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM161435(US10124003, Ex. Compound 49 | US10835536, Ex. Comp...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27XBQUS Patent