null

SMILES OC(=O)Cn1cc(Cc2nc3c(F)cccc3s2)c2ccccc12

InChI Key InChIKey=VMWZIBFOMSVTEY-UHFFFAOYSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16463   

TargetAldo-keto reductase family 1 member A1(Homo sapiens (Human))
The Institute for Diabetes Discovery

LigandPNGBDBM16463(2-{3-[(4-fluoro-1,3-benzothiazol-2-yl)methyl]-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QSNPubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
The Institute for Diabetes Discovery

LigandPNGBDBM16463(2-{3-[(4-fluoro-1,3-benzothiazol-2-yl)methyl]-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 6.6 T: 2°CAssay Description:The activity of the test enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappear...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38QSNPubMed