null

SMILES OC(COc1ncnc2ccccc12)CN1CCN(CC1)c1ccccc1F

InChI Key InChIKey=KFGMUASCSOBKRG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 167948   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167948(1-(4-(2-Fluorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 34.7nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167948(1-(4-(2-Fluorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 162nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetFibroblast growth factor 2(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167948(1-(4-(2-Fluorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 372nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

LigandPNGBDBM167948(1-(4-(2-Fluorophenyl)piperazin-1-yl)-3-(quinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 409nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB22TRPubMed