null

SMILES O[C@H]1CCn2c1c(O)n(-c1ccc(C#N)c3ccccc13)c2=O

InChI Key InChIKey=KCKSSZPSWNJGCS-AWEZNQCLSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18172   

TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM18172(4-[(7S,7aR)-7-hydroxy-1,3-dioxo-hexahydro-1H-pyrro...)copy SMILEScopy InChI
Affinity DataKi:  5.30nM ΔG°:  -11.2kcal/mole IC50: 60nM EC50:  1.30E+3nMpH: 7.4 T: 2°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DQ9PubMed