null

SMILES CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C(=O)Nc1ccccc1)-c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=PNRWKVJLHGHICL-KAYWLYCHSA-M

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18374   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Pfizer Global Research & Development

Curated by ChEMBL
LigandPNGBDBM18374(CHEMBL394937 | Pyrrole-based compound, 30 | sodium...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1K9QPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM18374(CHEMBL394937 | Pyrrole-based compound, 30 | sodium...)copy SMILEScopy InChI
Affinity DataIC50: 12nMpH: 7.2 T: 2°CAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3B7GPubMed