null

SMILES CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)C(O)=O)ccc1O

InChI Key InChIKey=TVQYCFFCYRSFQF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 18868   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)copy SMILEScopy InChI
Affinity DataIC50: 130nM EC50:  190nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)copy SMILEScopy InChI
Affinity DataIC50: 21nM EC50:  150nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26TGPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)copy SMILEScopy InChI
Affinity DataIC50: 20.9nMAssay Description:Inhibition of thyroid hormone receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XJQPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XJQPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Karo Bio AB

LigandPNGBDBM18868(3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...)copy SMILEScopy InChI
Affinity DataIC50: 20.9nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HD8PubMed