null

SMILES Cc1ccc(cc1C#N)C(=O)Nc1cnc2n(C)cc(C3CCN(CC3)C(=O)C3CCCC3)c2c1C(F)(F)F

InChI Key InChIKey=VFXNZJPVLBDCIY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 189873   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189873(US10227346, Example 2 | US10426135, Example 2 | US...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Specifically, in one embodiment the aforementioned assay was performed as outlined below. The assay was carried out in black polystyrene, 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28G8HWTUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189873(US10227346, Example 2 | US10426135, Example 2 | US...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189873(US10227346, Example 2 | US10426135, Example 2 | US...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9M91US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189873(US10227346, Example 2 | US10426135, Example 2 | US...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent