null

SMILES C[C@H](C(=O)N1CCC(CC1)c1cn(C)c2ncc(NC(=O)c3cccc(c3)C#N)c(c12)C(F)(F)F)C(C)(C)C

InChI Key InChIKey=HOYIABUVEXFNIV-QGZVFWFLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 189895   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189895(US10227346, Example 22 | US10426135, Example 22 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMpH: 7.5 T: 2°CAssay Description:Specifically, in one embodiment the aforementioned assay was performed as outlined below. The assay was carried out in black polystyrene, 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28G8HWTUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189895(US10227346, Example 22 | US10426135, Example 22 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189895(US10227346, Example 22 | US10426135, Example 22 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9M91US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189895(US10227346, Example 22 | US10426135, Example 22 | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent