null

SMILES Cn1cc(C2CCN(CC2)C(=O)C2CCCC2)c2c(c(NC(=O)c3cccc(c3)C#N)cnc12)C(F)(F)F

InChI Key InChIKey=NZNIPTPCNOREKS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 189897   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMpH: 7.5 T: 2°CAssay Description:Specifically, in one embodiment the aforementioned assay was performed as outlined below. The assay was carried out in black polystyrene, 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28G8HWTUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZGVUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The activity of compound of the invention can be determined by a co-activator recruitment by TR-FRET (time-resolved fluorescence resonance energy tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23N25QBUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Pfizer Inc.

US Patent
LigandPNGBDBM189897(US10227346, Example 23 | US10426135, Example 23 | ...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9M91US Patent