null

SMILES COC(=O)C(C(=O)\C=C\c1ccc(O)cc1)C(=O)\C=C\c1ccc(O)cc1

InChI Key InChIKey=QRIBEDBOVWHYJL-PWHKKFIBSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 191767   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Research Foundation of State University of New York; Chem-Master International, Inc.

US Patent
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0M3VUS Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York; Chem-Master International, Inc.

US Patent
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0M3VUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
The Research Foundation of State University of New York; Chem-Master International, Inc.

US Patent
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Research Foundation of State University of New York; Chem-Master International, Inc.

US Patent
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F47T2HUS Patent
TargetCollagenase 3 (MMP13)(Homo sapiens (Human))TBA
LigandPNGBDBM191767(US11608309, Compound 3 | US9187406, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0M3VUS Patent