null

SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@@H](O)c1ccsc1

InChI Key InChIKey=CEGTZPFCUQUJQF-PUHATCMVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19217   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM19217((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nM EC50:  1nMpH: 7.5 T: 2°CAssay Description:The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542KVJPubMed
LigandPNGBDBM19217((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)copy SMILEScopy InChI
Affinity DataEC50:  126nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H3NPubMed
LigandPNGBDBM19217((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with CCL2-promoter luciferase plasmid construct assessed as reducti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4H3NPubMed