null
SMILES Cn1cc(cn1)[C@@H](NC(=O)c1cc(F)c2cnc(NC3CCOCC3)nc2c1)c1cccc(F)c1
InChI Key InChIKey=JPKBESGDPJRCBB-QHCPKHFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 192388
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array BioPharma Inc.; Genentech, Inc.
US Patent
Array BioPharma Inc.; Genentech, Inc.
US Patent
Affinity DataIC50: 1.20nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1 [8-360](Homo sapiens (Human))
Array BioPharma Inc.; Genentech, Inc.
US Patent
Array BioPharma Inc.; Genentech, Inc.
US Patent
Affinity DataIC50: 1.30nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an N-terminal 6-His fusion pro...More data for this Ligand-Target Pair