null

SMILES CN(C)C(=O)C(=Cc1ccc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cc1)C#N

InChI Key InChIKey=PXDGIFGYVAPLCW-XNTDXEJSSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192809   

TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
PRINCIPIA BIOPHARMA, INC.

US Patent
LigandPNGBDBM192809(US9187487, 71)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMpH: 7.5 T: 2°CAssay Description:Phosphorylation of the appropriate peptide substrate (fluorescently labeled Srctide) by recombinant JAK3 (catalytic domain, aa 781-1124) was measured...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936B3US Patent