null

SMILES COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)C2CCNCC2)cc1

InChI Key InChIKey=MUMIOCPFGKBWRY-MGBGTMOVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 19331   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nM EC50:  3nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7SZ4PubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Agonist activity at human GHSR1a receptor expressed in CHO cells assessed as intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM586CPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)copy SMILEScopy InChI
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N0168ZPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Displacement of [125I]His9-ghrelin from human GHSR1a receptor expressed in LLC PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM586CPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Displacement of 125I-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N0168ZPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
CNRS

LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at human GHSR1a receptor expressed in CHO cells assessed as reduction of ghrelin-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM586CPubMed