null

SMILES ONC(=O)c1ccc(CNC(=O)c2nc(sc2C2CC2)-c2nccs2)cc1

InChI Key InChIKey=HPAOMQPZUJIWDB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 197366   

TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Puyi Chemical Co., Ltd.

US Patent
LigandPNGBDBM197366(US9216962, CFH401)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7G3FUS Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical Co., Ltd.

US Patent
LigandPNGBDBM197366(US9216962, CFH401)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7G3FUS Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Shanghai Puyi Chemical Co., Ltd.

US Patent
LigandPNGBDBM197366(US9216962, CFH401)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant His6/GST-tagged human HDAC3 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839VRPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shanghai Puyi Chemical Co., Ltd.

US Patent
LigandPNGBDBM197366(US9216962, CFH401)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant His6/GST-tagged human HDAC1 expressed in baculovirus infected High5 insect cells using Ac-Lys-Tyr-Lys(epsilon-acetyl)-AMC a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839VRPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM197366(US9216962, CFH401)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant His6/GST-tagged human HDAC6 expressed in baculovirus infected High5 insect cells using Boc-Lys(epsion-acetyl)-AMC as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839VRPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM197366(US9216962, CFH401)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Enzyme activity of HDAC1,3 is determined using the substrate Ac-Lys-Tyr-Lys(Ac)-AMC while the enzyme activity of HDAC6 is assayed using the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QJ7G3FUS Patent