null

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NC1COCC1=O

InChI Key InChIKey=GGNPRFIUKYTFLP-MLCCFXAWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 19798   

TargetCathepsin K(Homo sapiens (Human))
GSK

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)copy SMILEScopy InChI
Affinity DataKi:  140nM ΔG°:  -9.25kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F6CPubMed
TargetCathepsin K(Homo sapiens (Human))
GSK

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Inhibitory activity against human cysteine protease, cathepsin K.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZP45CQPubMed
TargetCathepsin S(Homo sapiens (Human))
GSK

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F6CPubMed
TargetProcathepsin L(Homo sapiens (Human))
GSK

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F6CPubMed
TargetCathepsin B(Homo sapiens (Human))
GSK

LigandPNGBDBM19798(3-amidotetrahydrofuran-4-one, 3 | CHEMBL61805 | be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nM ΔG°: >-6.75kcal/molepH: 5.5 T: 2°CAssay Description:Assays were carried out in the presence of variable concentrations of test compound. Reactions were initiated by addition of enzyme to buffered solut...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67F6CPubMed